Novel Small Molecule Drug Discovery Platform Harnesses Immune System to Defeat Cancers, Viral Infections and Inflammatory Diseases

摘要

More than 300 million patients worldwide are infected with hepatitis B virus (HBV). Each year, more than a million of these patients die from the virus, which is also major cause of liver cancer and cirrhosis. Worldwide, cancer claims the lives of millions more. Chronic HBV, cancer, and a variety of inflammatory diseases are caused by immune dysfunction at the cellular level. Now, the power of nucleic acid technology is being harnessed to design small molecule nucleic acid hybrid (SMNH) drugs that harness the patient's own immune system to defeat these cancers and cure viral diseases at global scales.