Diagnostic Value of 99m Tc- Labeled-Ubiquicidin 29-41 (99m Tc-UBI) Scan in the Diagnosis of Vertebral Osteomyelitis

摘要

Background: As world population gets older, more cases of collapse fracture, disc herniation, vertebral osteomyelitis and chord compression and surgeries on spine are noted. One of the complications is pain and in differential diagnosis are infectious and non-infectious processes. The method of choice for the diagnosis of infection in spinal column is MRI, however it is inapplicable in many cases. In addition, other imaging modalities like CT scan, PET or bone scintigraphy have their own limitations. UBI is a polypeptide which is taken by bacteria in the cell wall and therefore Tc99m-UBI has been used to detect infectious processes with promising results.