Evaluation of Tumor-Derived Exosomal miRNA as Potential Diagnostic Biomarkers for Early-Stage Non-Small Cell Lung Cancer Using Next-Generation Sequencing

Jin Xiance; Chen Yanfan; Chen Hanbin; Fei Shaoran; Chen Didi; Cai Xiaona; Liu Linger; Lin Baochai; Su Huafang; Zhao Lihao; Su Meng; Pan Huanle; Shen Lanxiao; Xie Deyao; Xie Congying

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Evaluation of Tumor-Derived Exosomal miRNA as Potential Diagnostic Biomarkers for Early-Stage Non-Small Cell Lung Cancer Using Next-Generation Sequencing

机译：利用下一代测序评估肿瘤衍生的外泌体miRNA作为早期非小细胞肺癌的潜在诊断生物标志物

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摘要

Purpose: To identify tumor-derived exosomal biomarkers that are able to discriminate between adenocarcinoma and squamous cell carcinoma (SCC) as a noninvasive method in the early diagnosis of non-small cell lung cancer (NSCLC).

机译：目的：鉴定能够区分腺癌和鳞状细胞癌（SCC）作为非小细胞肺癌（NSCLC）的非侵入性方法的肿瘤衍生的外泌体生物标志物。

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来源
《Clinical cancer research: an official journal of the American Association for Cancer Research》 |2017年第17期|共9页
作者
Jin Xiance; Chen Yanfan; Chen Hanbin; Fei Shaoran; Chen Didi; Cai Xiaona; Liu Linger; Lin Baochai; Su Huafang; Zhao Lihao; Su Meng; Pan Huanle; Shen Lanxiao; Xie Deyao; Xie Congying;
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作者单位

Wenzhou Med Univ Affiliated Hosp 1 Dept Radiotherapy &

Chemotherapy Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Resp Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Radiotherapy &

Chemotherapy Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Radiotherapy &

Chemotherapy Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Radiotherapy &

Chemotherapy Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Radiotherapy &

Chemotherapy Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Radiotherapy &

Chemotherapy Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Radiotherapy &

Chemotherapy Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Radiotherapy &

Chemotherapy Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Radiotherapy &

Chemotherapy Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Radiotherapy &

Chemotherapy Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Radiotherapy &

Chemotherapy Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Radiotherapy &

Chemotherapy Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Thorac Surg Wenzhou Peoples R China;

Wenzhou Med Univ Affiliated Hosp 1 Dept Radiotherapy &

Chemotherapy Wenzhou Peoples R China;

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正文语种 eng
中图分类肿瘤学;
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专利

1. Evaluation of Tumor-Derived Exosomal miRNA as Potential Diagnostic Biomarkers for Early-Stage Non-Small Cell Lung Cancer Using Next-Generation Sequencing [J] . Jin Xiance, Chen Yanfan, Chen Hanbin, Clinical cancer research: an official journal of the American Association for Cancer Research . 2017,第17期

机译：利用下一代测序评估肿瘤衍生的外泌体miRNA作为早期非小细胞肺癌的潜在诊断生物标志物
2. Integrative analysis of mRNA and miRNA expression profiles reveals seven potential diagnostic biomarkers for non-small cell lung cancer [J] . Oncology reports . 2020,第1期

机译：mRNA和miRNA表达谱的整合分析显示出用于非小细胞肺癌的七种潜在诊断生物标志物
3. Identification of serum miRNAs by nano-quantum dots microarray as diagnostic biomarkers for early detection of non-small cell lung cancer [J] . Fan Lihong, Qi Huiwei, Teng Junliang, Tumour biology : . 2016,第6期

机译：通过纳米量子点微阵列鉴定血清miRNAs作为诊断性生物标记物，用于早期检测非小细胞肺癌
4. An Integrated Approach for Profiling Potential Biomarkers in Human Plasma to Detection Non-small Cell Lung Cancer [C] . Valeriy E. Shevchenko, Irina B. Zborovskaya, Natalia E. Arnotskaya, ASMS Conference on Mass Spectrometry and Allied Topics . 2006

机译：一种分析人血浆中潜在生物标志物检测非小细胞肺癌的综合方法
5. Pharmacological Evaluation of a Synthetic Coumarin Derivative (4-Fluorophenylacetamide-Acetyl Coumarin) for Its Potential Anticancer Activity in Non-Small Cell Lung Cancer Cell Line [D] . Umar, Shweta. 2020

机译：合成香豆素衍生物（4-氟苯乙酰胺 - 乙酰氨基甲酸）在非小细胞肺癌细胞系中抗癌活性的药理评价
6. Tumor-Derived Exosomal miRNAs as Diagnostic Biomarkers in Non-Small Cell Lung Cancer [O] . Zhijun Zhang, Youyong Tang, Xingguo Song, 2020

机译：肿瘤衍生的外泌体MiRNA作为非小细胞肺癌的诊断生物标志物
7. Tumor-Derived Exosomal miRNAs as Diagnostic Biomarkers in Non-Small Cell Lung Cancer [O] . Zhijun Zhang, Youyong Tang, Xingguo Song, 2020

机译：肿瘤衍生的外泌体MiRNA作为非小细胞肺癌的诊断生物标志物

Evaluation of Tumor-Derived Exosomal miRNA as Potential Diagnostic Biomarkers for Early-Stage Non-Small Cell Lung Cancer Using Next-Generation Sequencing

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