Lacosamide treatment of childhood refractory focal epilepsy: the first reported side effect in paediatric patients

Yildiz Edibe Pembegul; Ozkan Melis Ulak; Bektas Gonca; Uzunhan Tugce Aksu; Aydinli Nur; Caliskan Mine; Ozmen Meral

首页> 外文期刊>Child's nervous system: ChNS : official journal of the International Society for Pediatric Neurosurgery >Lacosamide treatment of childhood refractory focal epilepsy: the first reported side effect in paediatric patients

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Lacosamide treatment of childhood refractory focal epilepsy: the first reported side effect in paediatric patients

机译：儿童难治性焦点癫痫的漆酰胺治疗：第一次报告的儿科患者副作用

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Lacosamide (LCM) is an effective antiepileptic drug (AED) approved for the treatment of focal epilepsy in both children and adults. The aim of this observational study was to review our centre's experience with LCM and to characterise its efficacy and tolerability as an adjunct therapy in children with refractory focal epilepsy.

机译：漆酰胺（LCM）是批准用于治疗儿童和成人局灶性癫痫的有效抗癫痫药物（AED）。该观察项研究的目的是审查我们的中心的LCM经验，并将其疗效和耐受性表征为难治局灶性癫痫儿童的辅助治疗。

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《Child's nervous system: ChNS : official journal of the International Society for Pediatric Neurosurgery》 |2017年第11期|共5页
作者
Yildiz Edibe Pembegul; Ozkan Melis Ulak; Bektas Gonca; Uzunhan Tugce Aksu; Aydinli Nur; Caliskan Mine; Ozmen Meral;
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作者单位

Istanbul Univ Istanbul Fac Med Dept Pediat Div Pediat Neurol TR-34093 Istanbul Turkey;

Istanbul Univ Istanbul Fac Med Dept Pediat Div Pediat Neurol TR-34093 Istanbul Turkey;

Istanbul Univ Istanbul Fac Med Dept Pediat Div Pediat Neurol TR-34093 Istanbul Turkey;

Istanbul Univ Istanbul Fac Med Dept Pediat Div Pediat Neurol TR-34093 Istanbul Turkey;

Istanbul Univ Istanbul Fac Med Dept Pediat Div Pediat Neurol TR-34093 Istanbul Turkey;

Istanbul Univ Istanbul Fac Med Dept Pediat Div Pediat Neurol TR-34093 Istanbul Turkey;

Istanbul Univ Istanbul Fac Med Dept Pediat Div Pediat Neurol TR-34093 Istanbul Turkey;

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正文语种 eng
中图分类神经病学与精神病学;
关键词
Lacosamide; Status epilepticus; Childhood; Focal epilepsy;

机译：漆酰胺;状态癫痫;童年;焦点癫痫;

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专利

1. Lacosamide treatment of childhood refractory focal epilepsy: the first reported side effect in paediatric patients [J] . Yildiz Edibe Pembegul, Ozkan Melis Ulak, Bektas Gonca, Child's nervous system: ChNS : official journal of the International Society for Pediatric Neurosurgery . 2017,第11期

机译：儿童难治性焦点癫痫的漆酰胺治疗：第一次报告的儿科患者副作用
2. Cost effectiveness of lacosamide in the adjunctive treatment of patients with refractory focal epilepsy in Belgium [J] . SimoensS., DeNaeyerL., DedekenP. CNS drugs . 2012,第4期

机译：拉可酰胺在比利时难治性局灶性癫痫患者辅助治疗中的成本效益
3. Effect of lacosamide on depression and anxiety symptoms in patients with focal refractory epilepsy: A prospective multicenter study [J] . Rocamora Rodrigo, Ley Miguel, Molins Albert, Epilepsy & behavior: E&B . 2018,第期

机译：涂层酰胺对局灶性难治性癫痫患者抑郁和焦虑症状的影响：临床多中心研究
4. Background activity originating from same area as events in the EEG of paediatric patients with focal epilepsy [C] . Vanrumste B., Jones R.D., Bones P.J., Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE . -1

机译：背景活动与小儿局灶性癫痫患者脑电图的事件起源于同一区域
5. Quantitative analysis of EEG for the detection and localization of seizures in patients with medically refractory epilepsy. [D] . Battiston, John Joseph, Jr. 1999

机译：脑电图定量分析以检测和定位难治性癫痫患者的癫痫发作。
6. Lacosamide may improve cognition in patients with focal epilepsy: EpiTrack to compare cognitive side effects of lacosamide and carbamazepine [O] . Claudio Liguori, Francesca Izzi, Natalia Manfredi, 2018

机译：Lacosamide可能会改善局灶性癫痫患者的认知能力：EpiTrack可以比较Lacosamide和卡马西平的认知副作用
7. Early clinical experience with lacosamide as adjunctive therapy in patients with refractory focal epilepsy and nocturnal seizures [O] . García-Morales Irene, Delgado Rafael Toledano, Falip Mercé, 2011

机译：Lacosamide作为辅助治疗难治性局灶性癫痫和夜间发作的早期临床经验

Lacosamide treatment of childhood refractory focal epilepsy: the first reported side effect in paediatric patients

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