A new framework for conceptualizing symptoms in frontotemporal dementia: from animal models to the clinic

摘要

Behavioural-variant frontotemporal dementia is characterised by a number of seemingly disparate clinical features. On the basis of evidence from animal studies, functional neuroimaging and behavioural neurology, Wong et al. propose that these symptoms reflect a common underlying disturbance in the capacity for goal-directed behaviour and the concomitant emergence of habits.