A Sensitive Method for Detecting Zika Virus Antigen in Patients' Whole-Blood Specimens as an Alternative Diagnostic Approach

Lum Fok-Moon; Lin Cui; Susova Olga Y.; Teo Teck-Hui; Fong Siew-Wai; Mak Tze-Minn; Lee Linda Kay; Chong Chia-Yin; Lye David C. B.; Lin Raymond T. P.; Merits Andres; Leo Yee-Sin; Ng Lisa F. P.

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A Sensitive Method for Detecting Zika Virus Antigen in Patients' Whole-Blood Specimens as an Alternative Diagnostic Approach

机译：一种敏感方法，用于检测患者全血标本中ZIKA病毒抗原作为替代诊断方法

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Background. Epidemics caused by the reemergence of Zika virus (ZIKV) warrant the need to develop new diagnostic measures to complement currently used detection methods. In this study, we explored the detection of ZIKV antigen in a defined leukocyte subset from patients' whole-blood specimens.

机译：背景。 Zika病毒（ZIKV）的重新调查引起的流行病值得需要开发新的诊断措施，以补充目前使用的检测方法。在这项研究中，我们探讨了患者全血样本的定义白细胞子集中的ZIKV抗原的检测。

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来源
《The Journal of Infectious Diseases》 |2017年第2期|共9页
作者
Lum Fok-Moon; Lin Cui; Susova Olga Y.; Teo Teck-Hui; Fong Siew-Wai; Mak Tze-Minn; Lee Linda Kay; Chong Chia-Yin; Lye David C. B.; Lin Raymond T. P.; Merits Andres; Leo Yee-Sin; Ng Lisa F. P.;
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作者单位

Agcy Sci Technol &

Res Singapore Immunol Network Singapore Singapore;

Minist Hlth Natl Publ Hlth Lab Singapore Singapore;

Minist Hlth Russian Federat Blokhin Russian Canc Res Ctr Moscow Russia;

Agcy Sci Technol &

Res Singapore Immunol Network Singapore Singapore;

Agcy Sci Technol &

Res Singapore Immunol Network Singapore Singapore;

Minist Hlth Natl Publ Hlth Lab Singapore Singapore;

Tan Tock Seng Hosp Inst Infect Dis &

Epidemiol Singapore Singapore;

KK Womens &

Childrens Hosp Singapore Singapore;

Tan Tock Seng Hosp Inst Infect Dis &

Epidemiol Singapore Singapore;

Minist Hlth Natl Publ Hlth Lab Singapore Singapore;

Univ Tartu Inst Technol Tartu Estonia;

Natl Univ Singapore Saw Swee Hock Sch Publ Hlth Singapore Singapore;

Agcy Sci Technol &

Res Singapore Immunol Network Singapore Singapore;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
Zika virus; monocytes; detection; diagnosis;

机译：Zika病毒;单核细胞;检测;诊断;

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专利

1. A Sensitive Method for Detecting Zika Virus Antigen in Patients' Whole-Blood Specimens as an Alternative Diagnostic Approach [J] . Lum Fok-Moon, Lin Cui, Susova Olga Y., The Journal of Infectious Diseases . 2017,第2期

机译：一种敏感方法，用于检测患者全血标本中ZIKA病毒抗原作为替代诊断方法
2. Improved detection of Zika virus RNA in human and animal specimens by a novel, highly sensitive and specific real-time RT-PCR assay targeting the 5'-untranslated region of Zika virus [J] . Chan Jasper Fuk-Woo, Yip Cyril Chik-Yan, Tee Kah-Meng, Tropical Medicine and International Health: TM and IH . 2017,第5期

机译：通过新颖的，高度敏感的和特异性实时RT-PCR测定改善了人和动物标本中的Zika病毒RNA检测，靶向Zika病毒的5'-Unranslated区域
3. Diagnostic Validation of the RealStar (R) Zika Virus Reverse Transcription Polymerase Chain Reaction Kit for Detection of Zika Virus RNA in Urine and Serum Specimens [J] . Oelschlaeger Stephan, Enfissi Antoine, Zaruba Mareen, The American Journal of Tropical Medicine and Hygiene . 2017,第4期

机译：真实序列（R）Zika病毒逆转录聚合酶链反应试剂盒检测尿液和血清标本中Zika病毒RNA的诊断验证
4. Evaluation of Flu DETECT antigen test kit using three different sampling methods during natural infections of influenza A virus in swine [C] . Joseph P. Yaros, Brett K. OBrien, Joel L. Nerem, American Association of Swine Veterinarians Annual Meeting . 2015

机译：利用三种不同抽样方法评价流感检测抗原试剂盒在猪流感病毒自然感染期间
5. Characterization of gamma herpesvirus viral DNA in peripheral blood of patients with virus-associated malignancies and analysis of CD8+ T cell responses to viral antigens in patients with Hodgkin's lymphoma. [D] . Lin, Lan. 2005

机译：霍乱金淋巴瘤患者病毒相关恶性肿瘤患者外周血中γ疱疹病毒DNA的表征以及CD8 + T细胞对病毒抗原的应答分析。
6. A Sensitive Method for Detecting Zika Virus Antigen in Patients’ Whole-Blood Specimens as an Alternative Diagnostic Approach [O] . Fok-Moon Lum, Cui Lin, Olga Y Susova, -1

机译：一种检测患者全血标本中寨卡病毒抗原的灵敏方法作为替代诊断方法
7. A Sensitive Method for Detecting Zika Virus Antigen in Patients’ Whole-Blood Specimens as an Alternative Diagnostic Approach [O] . Fok-Moon Lum, Cui Lin, Olga Y Susova, 2017

机译：一种敏感方法，用于检测患者全血标本中ZIKA病毒抗原作为替代诊断方法

A Sensitive Method for Detecting Zika Virus Antigen in Patients' Whole-Blood Specimens as an Alternative Diagnostic Approach

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