Adverse effects of antioxidants

摘要

The letter on 'adverse effects of antioxi-dants' referring to an earlier report was interesting. However, the nature of adverse effects expected from consuming an-tioxidants (rich preparations), beta-carotene or vitamin-E as antioxidants was not clearly illustrated. Rather, their therapeutic application based on antioxidant properties is being increasingly advocated for beneficial effects in various disease conditions. The importance of antioxidants, their mechanisms of action and the paradox related to beta-carotene and vitamin-E are available in the literature. Furthermore, vitamin-E, etc. have provided important insights into the design and development of novel therapeutics based on antioxidant mechanisms. Several views advocating the development of antioxidant-based drugs have provided various positive points in rationalizing their development for the treatment of diseases of multifactorial origin.