Synthesis and in vitro characterization of a preactivated thiolated acrylic acid/acrylamide-methylpropane sulfonic acid copolymer as a mucoadhesive sprayable polymer

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Synthesis and in vitro characterization of a preactivated thiolated acrylic acid/acrylamide-methylpropane sulfonic acid copolymer as a mucoadhesive sprayable polymer

机译：磷粘附可喷涂聚合物的预活性硫醇丙烯酸/丙烯酰胺 - 甲基丙烷磺酸共聚物的合成及体外表征

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Aim: Development of a preactivated thiomer as sprayable excipient for mucoadhesive formulations.

机译：目的：开发粘膜粘附配方的可喷雾剂的硫聚物。

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《International Journal of Pharmaceutics》 |2020年第2020期|共7页
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正文语种 eng
中图分类药学;
关键词
Thiomer; Preactivated Thiomer; Mucoadhesion; Sprayable excipient;

机译：巯基;失活的巯基;粘膜粘合剂;可喷赋形剂;

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1. Synthesis and in vitro characterization of a preactivated thiolated acrylic acid/acrylamide-methylpropane sulfonic acid copolymer as a mucoadhesive sprayable polymer [J] . International Journal of Pharmaceutics . 2020,第期

机译：磷粘附可喷涂聚合物的预活性硫醇丙烯酸/丙烯酰胺 - 甲基丙烷磺酸共聚物的合成及体外表征
2. Amphiphilic gradient poly(styrene-co-acrylic acid) copolymer prepared via nitroxide-mediated solution polymerization.Synthesis,characterization in aqueous solution and evaluation as emulsion polymerization stabilizer [J] . Catherine Lefay, Bernadette Charleux, Maud Save, Polymer: The International Journal for the Science and Technology of Polymers . 2006,第6期

机译：氮氧化物介导的溶液聚合制备的两亲梯度聚（苯乙烯-丙烯酸）共聚物。在水溶液中的合成，表征及作为乳液聚合稳定剂的评价
3. Block copolymers of acrylic acid and butyl acrylate prepared by reversible addition-fragmentation chain transfer polymerization: Synthesis, characterization, and use in emulsion polymerization [J] . Gaillard N., Guyot A., Claverie J. Journal of Polymer Science, Part A. Polymer Chemistry . 2003,第5期

机译：可逆加成-断裂链转移聚合制备的丙烯酸和丙烯酸丁酯的嵌段共聚物：合成，表征和在乳液聚合中的应用
4. Mucoadhesive thiolated polymers: synthesis and in vitro evalaution of chitosan-thiogcolic acid conjugates [C] . C.E.Kast, J.Freudl, A.Bernkop-Schnuerch International symposium on controlled release of bioactive materials;Consumer and diversified products conference . 2000

机译：粘膜粘附硫醇化聚合物：壳聚糖-巯基乙酸共轭物的合成和体外评价
5. Synthesis, characterization and applications of a new redox -active polymer based on ABTS [2,2'-azino-bis(3-ethylbenzothaizoline-6-sulfonic acid)]. [D] . Fei, Jiangfeng. 2007

机译：基于ABTS [2,2'-叠氮基双（3-乙基苯并噻唑啉-6-磺酸）]的新型氧化还原活性聚合物的合成，表征和应用。
6. Polymer Electrolyte Membranes Prepared by Graft Copolymerization of 2-Acrylamido-2-Methylpropane Sulfonic Acid and Acrylic Acid on PVDF and ETFE Activated by Electron Beam Treatment [O] . Xi Ke, Yufei Zhang, Uwe Gohs, 2019

机译：通过电子束处理活化的2-氟丙烯酰胺基-2-甲基丙烷磺酸和丙烯酸在PVDF和ETFE上的接枝共聚反应制备的高分子电解质膜
7. Synthesis and Characterization Superabsorbent Polymers Made of Starch, Acrylic Acid, Acrylamide, Poly(Vinyl Alcohol), 2-Hydroxyethyl Methacrylate, 2-Acrylamido-2-methylpropane Sulfonic Acid [O] . Elżbieta Czarnecka, Jacek Nowaczyk 2021

机译：由淀粉，丙烯酸，丙烯酰胺，聚（乙烯醇），2-羟乙基甲酸甲酯，2-丙烯酰胺-2-甲基丙烷磺酸制成的合成和表征超吸收性聚合物
8. Water-Soluble Copolymers. 53. (23)Na NMR Studies of Hydrophobically-ModifiedPolyacids: Copolymers of 2-(1-Naphthylacetamido) ethylacrylamide with Acrylic Acid and Methacrylic Acid [R] . Newman, J. K., McCormick, C. L. 1994

机译：水溶性共聚物。 53.（23）疏水改性多酸的Na NmR研究：2-（1-萘基乙酰氨基）乙基丙烯酰胺与丙烯酸和甲基丙烯酸的共聚物

Synthesis and in vitro characterization of a preactivated thiolated acrylic acid/acrylamide-methylpropane sulfonic acid copolymer as a mucoadhesive sprayable polymer

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