NEW users of non-steroidal anti-inflammatory drugs (NSAIDs) run a 40 to 70 per cent increased risk of developing atrial fibrillation (AF) or flutter, according to results of a large Danish case-control study, published online in the BMJ (4 July 2011). The findings add to those of a previous UK primary care study linking traditional NSAIDs to atrial fibrillation, and they also show that cyclo-oxygenase (COX) 2 inhibitors carry more risk that non-selective NSAIDs.
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