Pathology of human H5N1 infection: new findings

摘要

Human cases of the highly pathogenic avian influenza virus H5N1 were first documented in Hong Kong in 1997-From late 2003, this disease became endemic in Asia, often but not invariably associated with an outbreak in poultry. According to WHO, the total number of cases reported from 12 countries until July 25, 2007, was 319, with a fatality rate of 60?Sporadic cases of person-to-person transmission have been reported and a pandemic outbreak poses a serious threat. The table summarises the results of the few postmortem studies after human H5N1 infection. In today's Lancet, Jiang Gu and colleagues report new findings from two postmortem studies in people who had H5N1, including a rare case of a preg nant woman and her fetus