Efficient microwave-assisted synthesis of new sulfonylbenzimidazole-4,7-diones: heterocyclic quinones with potential antitumor activity

Boufatah N; Gellis A; Maldonado J; Vanelle P

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Efficient microwave-assisted synthesis of new sulfonylbenzimidazole-4,7-diones: heterocyclic quinones with potential antitumor activity

机译：有效的微波辅助合成新磺酰基苯并咪唑-4,7-二酮类化合物：具有潜在抗肿瘤活性的杂环醌

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New benzimidazoloquinones substituted at 2-position by a sulfonyl group have been synthesized via a final microwave assisted step using 2-chloromethyl-1,5,6-trimethylbenzimidazole-4,7-dione 7 as starting material. (C) 2004 Elsevier Ltd. All rights reserved.

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《Tetrahedron》 |2004年第41期|共7页
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Boufatah N; Gellis A; Maldonado J; Vanelle P;
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benzimidazole-4; 7-diones; microwave irradiation; S-alkylation; sulfones; BENZIMIDAZOLE-4; 7-DIONE DERIVATIVES; ANTIPROLIFERATIVE ACTIVITY; ORGANIC-REACTIONS; DRUG DISCOVERY; IRRADIATION; AGENTS; DNA; ALKYLATION; CHEMISTRY; SOLVENT;

机译：苯并咪唑-4;7-二酮;微波辐射;S-烷基化;砜;苯并咪唑-4;7-二酮衍生物;抗酸活性;有机反应;药物发现;辐照;试剂;DNA;烷基化;化学;溶剂;

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1. Efficient microwave-assisted synthesis of new sulfonylbenzimidazole-4,7-diones: heterocyclic quinones with potential antitumor activity [J] . Boufatah N, Gellis A, Maldonado J, Tetrahedron . 2004,第41期

机译：有效的微波辅助合成新磺酰基苯并咪唑-4,7-二酮类化合物：具有潜在抗肿瘤活性的杂环醌
2. Synthesis of Selenium-Quinone Hybrid Compounds with Potential Antitumor Activity via Rh-Catalyzed C-H Bond Activation and Click Reactions [J] . Guilherme Jardim, Daisy Lima, Wagner Valen?a, Molecules . 2018,第1期

机译：通过Rh催化的C-H键活化和Click反应合成具有潜在抗肿瘤活性的硒醌醌化合物
3. Microwave-Assisted Synthesis of Novel Pyrazolo[3,4-g][1,8]naphthyridin-5-amine with Potential Antifungal and Antitumor Activity [J] . Acosta Paola, Butassi Estefania, Insuasty Braulio, Molecules . 2015,第5期

机译：微波辅助合成具有潜在抗真菌和抗肿瘤活性的新型吡唑并[3,4-g] [1,8]萘啶-5-胺
4. Microwave-assisted synthesis of alkynylphenols and their conversion into heterocyclic compounds and prenylpolyphenols(Abstracts) [C] . Masao Tsukayama, Akishi Ninomiya, Yukiko Ohkushi European Symposium on Organic Chemistry . 2007

机译：微波辅助合成炔基苯酚及其转化成杂环化合物和戊基聚合物（摘要）
5. Part I. Nucleic acid site-selective binding studies of isomers of dihydrodioxin-masked ortho-quinones as potential antitumor drugs. Part II. The role of non-Watson-Crick base pairs in stabilizing a recurrent RNA motif . [D] . Khisamutdinov, Emil F. 2012

机译：第一部分。二氢二恶英掩盖的邻醌作为潜在抗肿瘤药物的异构体的核酸位点选择性结合研究。第二部分非Watson-Crick碱基对在稳定复发性RNA基序中的作用。
6. Microwave-Assisted Synthesis of Novel Pyrazolo34-g18naphthyridin-5-amine with Potential Antifungal and Antitumor Activity [O] . Paola Acosta, Estefanía Butassi, Braulio Insuasty, 2015

机译：微波辅助合成具有潜在抗真菌和抗肿瘤活性的新型吡唑并34-g 18萘啶-5-胺
7. Heterocyclic quinones. XVI. Pharmacomodulation in the series of 11H-indolo(3,2-c)quinolinediones: Synthesis, cytotoxicity and antitumor activity of 3-substituted 11H-pyrido(3',4':4,5)pyrrolo(3,2-c)quinoline-1,4-diones. [O] . Phillippe HELISSEY, Sylviane GIORGI-RENAULT, Jean RENAULT, 1989

机译：杂环Quinones。 XVI。 11H- Indolo（3,2-C）喹啉（3,2-C）喹啉（3,2-C）的药物调节：3取代的11H-吡啶（3'，4'：4,5）吡咯（3,2-C）喹啉的合成，细胞毒性和抗肿瘤活性-1,4-致力。

Efficient microwave-assisted synthesis of new sulfonylbenzimidazole-4,7-diones: heterocyclic quinones with potential antitumor activity

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