Skewness of Fractional Anisotropy Detects Decreased White Matter Integrity Resulting From Acute Optic Neuritis

摘要

PURPOSE. Diffusion tensor imaging (DTI) has demonstrated optic nerve damage associated with optic neuritis (ON); however, the usefulness of mean fractional anisotropy (FA) specifically is varied in the literature. We wished to determine whether histogram analysis of FA better detects ON damage than mean FA.