Chemical modification of porous calcium hydroxyapatite surfaces by grafting phenylphosphonic and phenylphosphite acids

摘要

It is well known that the incorporation of organic molecules can provide an effective route to modify the surface properties of apatite ceramics. The present study shows that phosphonates can react with calcium ions to control the formation of the hydroxyapatite structures. The grafting of C6H5PO(OH)(2) (PPOH) and C6H5PC(OH)H (PPH) was used to increase the specific surface area as well as the porosity of hydroxyapatite materials. The higher specific surface area for HAp treated by PPOH is around 267 m(2)/g compared to the pure HAp (140 m(2)/g). The phenyl (C6H5) groups are removed by thermal treatment around 500 degrees C. After treatment at 800 degrees C, organoapatites (PP-HAp) are converted to stoiochiometric hydroxyapatites. (c) 2006 Elsevier B.V. All rights reserved.