Paraneoplastic cerebellar syndrome and sensory ganglionopathy with papillary thyroid carcinoma

摘要

Paraneoplastic neurological disorders (PND) are syndromes caused by an autoimmune pathogenesis against 'onconeural antigens' shared between a tumour and the nervous system [1 ]. They are rare but important and can cause severe neurologic disability if not recognised and treated early. In addition, their clinical presentation often precedes identification of the associated cancer and alerts the physician to perform a thorough search for malignancy [2]. Here we describe the first reported case of cerebellar syndrome and sensory ganglionopathy as paraneoplastic phenomena in association with papillary thyroid carcinoma.