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Role of MYC-Regulated Long Noncoding RNAs in Cell Cycle Regulation and Tumorigenesis

机译:MYC调控的长非编码RNA在细胞周期调控和肿瘤发生中的作用。

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摘要

Background: The functions of long noncoding RNAs (lncRNAs) have been identified in several cancers, but the roles of lncRNAs in colorectal cancer (CRC) are less well understood. The transcription factor MYC is known to regulate lncRNAs and has been implicated in cancer cell proliferation and tumorigenesis.
机译:背景:长非编码RNA(lncRNA)的功能已在几种癌症中得到鉴定,但是lncRNA在结肠直肠癌(CRC)中的作用尚不清楚。已知转录因子MYC调节lncRNA,并与癌细胞增殖和肿瘤发生有关。

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