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首页> 外文期刊>Journal of the American College of Surgeons >Current indication of a modified Sugiura procedure in the management of variceal bleeding.
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Current indication of a modified Sugiura procedure in the management of variceal bleeding.

机译:目前在处理静脉曲张破裂出血中采用改良的Sugiura手术的指征。

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BACKGROUND: The role of gastroesophageal devascularization (Sugiura-rype procedures) for the treatment of variceal bleeding remains controversial. Although Japanese series reported favorable longterm results, the technique has nor been widely accepted in the Western Hemisphere because of a high postoperative morbidity and mortality. The reasons for the different outcomes are unclear. In a multidisciplinary team approach we developed a therapeutic algorithm for patients with recurrent variceal bleeding. STUDY DESIGN: The Sugiura procedure was offered only to patients with well-preserved liver function (Child A or Child B cirrhosis without chronic ascites) who were not candidates for distal splenorenal shunt, transhepatic porto-systemic shunt, or liver transplantation. RESULTS: Fifteen patients with recurrent variceal bleeding underwent a modified Sugiura procedure between September 1994 and September 1997. All but one patient (operative mortality 7%) are alive after a median followup of 4 years. Recurrent variceal bleeding developed in one patient; esophageal strictures, which were successfully treated by endoscopic dilatation, developed in three patients; and one patient experienced mild encephalopathy. Major complications were noted only in patients with impaired liver function (Child B cirrhosis) or when the modified Sugiura was performed in an emergency setting. The presence of cirrhosis or the cause of portal hypertension had no significant impact on the complication rate. CONCLUSIONS: This series was performed during the last decade when all modern therapeutic options for variceal bleeding were available. Our results indicate that the modified Sugiura procedure is an effective rescue therapy in patients who are not candidates for selective shunts, transhepatic porto-systemic shunt, or transplantation. Emergency settings and decreased liver function are associated with an increased morbidity.
机译:背景:胃食管反血管化(Sugiura-rype手术)在治疗静脉曲张破裂出血中的作用仍存在争议。尽管日本系列报道了良好的长期效果,但由于术后发病率和死亡率高,该技术在西半球尚未得到广泛接受。结果不同的原因尚不清楚。在一个多学科团队的方法中,我们为复发性静脉曲张破裂出血的患者开发了一种治疗算法。研究设计:Sugiura手术仅适用于肝功能良好的患者(儿童A或儿童B肝硬化,无慢性腹水),不适合进行远端脾肾分流术,经肝门-系统分流术或肝移植。结果:1994年9月至1997年9月间,对15例复发性静脉曲张破裂出血患者进行了改良的Sugiura手术。中位随访4年后,除1例患者(手术死亡率7%)外,其他患者均存活。一名患者复发性静脉曲张破裂出血; 3例患者出现了通过内镜扩张术成功治疗的食管狭窄;一名患者出现轻度脑病。仅在肝功能受损(Child B肝硬化)或在紧急情况下进行改良Sugiura的患者中发现主要并发症。肝硬化的存在或门脉高压的病因对并发症发生率没有显着影响。结论:该系列研究是在最近十年进行的,用于所有现代治疗静脉曲张破裂出血的方法。我们的结果表明,改良的Sugiura手术对不适合选择性分流,经肝门-系统分流或移植的患者是一种有效的抢救疗法。紧急情况和肝功能下降与发病率增加有关。

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