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A single-center, retrospective analysis evaluating the utilization of the opioid risk tool in opioid-treated cancer patients

机译:一项单中心回顾性分析,评估在阿片类药物治疗的癌症患者中使用阿片类药物风险工具的情况

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The Opioid Risk Tool (ORT) is a screening tool used to assess risk of opioid misuse by stratifying aberrant drug-seeking behaviors and/or identifying known risk factors for drug abuse. The objectives of this study were to risk stratify opioid misuse in a cancer pain population and determine the most common patient risk factors associated with misuse utilizing the ORT. This was a retrospective analysis conducted at an academic comprehensive cancer center. Patients were referred by an oncologist or hematologist to an outpatient palliative care clinic. One-hundred and fourteen patients with cancer (n = 107) or sickle cell disease (n = 7) were evaluated from July 2012 to July 2013. During the clinical interview, patients responded to a clinician administered ORT. Based on the ORT score, patients were stratified into low, moderate, or high risk for opioid misuse. Sample size included 57 men and 57 women. Sixty-five, 21, and 28 patients were deemed low, moderate, and high risk based on the ORT, respectively. The most common risk factors for opioid misuse were a history of depression (women = 32; men = 22) and family history of alcohol abuse (women = 26; men = 22). There was no difference between men and women in the prevalence of depression (P =.17) or family history of alcohol abuse (P =.57). The least common risk factor was a personal history of prescription drug abuse (n = 1) in women and history of preadolescent sexual abuse in men (n = 0). Twenty-five percent (n = 28) of the sample population were deemed high risk based on the ORT. Screening of cancer patients in the palliative care setting suggests that risk factors for opioid misuse exist. Stratifying patients based on a routine screening tool may help identify cancer patients at risk for aberrant drug behaviors.
机译:阿片类药物风险工具(ORT)是一种筛查工具,用于通过分层异常的药物寻找行为和/或识别已知的药物滥用危险因素来评估阿片类药物滥用的风险。这项研究的目的是对癌症疼痛人群中的阿片类药物滥用进行分层风险,并确定与ORT滥用相关的最常见患者危险因素。这是在学术综合癌症中心进行的回顾性分析。肿瘤科医生或血液科医生将患者转诊至门诊姑息治疗诊所。从2012年7月至2013年7月对141例癌症(n = 107)或镰状细胞病(n = 7)患者进行了评估。在临床访谈期间,患者对接受ORT的临床医生有反应。根据ORT评分,将患者分为阿片类药物滥用的低,中或高风险。样本量包括57名男性和57名女性。根据ORT,分别将65例,21例和28例患者视为低,中和高风险。阿片类药物滥用的最常见危险因素是抑郁史(女性= 32;男性= 22)和酗酒家族史(女性= 26;男性= 22)。抑郁症的患病率(P = .17)或酗酒家族史(P = .57)在男女之间没有差异。最不常见的危险因素是女性的个人处方药滥用史(n = 1)和男性的青春期前性虐待史(n = 0)。根据ORT,有25%(n = 28)的样本人群被认为是高危人群。在姑息治疗环境中对癌症患者进行筛查表明存在阿片类药物滥用的危险因素。基于常规筛查工具对患者进行分层可能有助于识别处于药物异常行为风险中的癌症患者。

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