Subconjunctival Injection of XG-102, a JNK Inhibitor Peptide, in Patients with Intraocular Inflammation: A Safety and Tolerability Study

Beydoun Talal; Deloche Catherine; Perino Julien; Kirwan Bridget-Anne; Combette Jean-Marc; Behar-Cohen Francine

首页> 外文期刊>Journal of ocular pharmacology and therapeutics: The official journal of the Association for Ocular Pharmacology and Therapeutics >Subconjunctival Injection of XG-102, a JNK Inhibitor Peptide, in Patients with Intraocular Inflammation: A Safety and Tolerability Study

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Subconjunctival Injection of XG-102, a JNK Inhibitor Peptide, in Patients with Intraocular Inflammation: A Safety and Tolerability Study

机译：眼内炎患者结膜下注射JG抑制剂肽XG-102的安全性和耐受性研究

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Purpose: We aimed to investigate the safety, tolerability, and systemic diffusion of a single escalating dose of XG-102 (a 31-D-amino-acid peptide inhibiting JNK pathway activation), administered subconjunctivally in the treatment of post-surgery or post-trauma intraocular inflammation.

机译：目的：我们旨在研究结膜下在手术后或手术后结膜下给予的单次递增剂量的XG-102（一种抑制JNK途径活化的31-D-氨基酸肽）的安全性，耐受性和全身扩散-创伤眼内炎症。

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《Journal of ocular pharmacology and therapeutics: The official journal of the Association for Ocular Pharmacology and Therapeutics》 |2015年第2期|共7页
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Beydoun Talal; Deloche Catherine; Perino Julien; Kirwan Bridget-Anne; Combette Jean-Marc; Behar-Cohen Francine;
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中图分类药理学;
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1. Subconjunctival Injection of XG-102, a JNK Inhibitor Peptide, in Patients with Intraocular Inflammation: A Safety and Tolerability Study [J] . Beydoun Talal, Deloche Catherine, Perino Julien, Journal of ocular pharmacology and therapeutics: The official journal of the Association for Ocular Pharmacology and Therapeutics . 2015,第2期

机译：眼内炎患者结膜下注射JG抑制剂肽XG-102的安全性和耐受性研究
2. Postoperative Ocular Inflammation: A Single Subconjunctival Injection of XG-102 Compared to Dexamethasone Drops in a Randomized Trial [J] . Chiquet Christophe, Aptel Florent, Creuzot-Garcher Catherine, American Journal of Ophthalmology: The International Journal of Ophthalmology . 2017,第期

机译：术后眼镜炎症：与随机试验中的地塞米松滴剂相比，XG-102的单个亚诊断注射
3. Effect of subconjunctival steroid injection on intraocular inflammation and blood glucose level after cataract surgery in diabetic patients. [J] . Fukushima H, Kato S, Kaiya T, Journal of cataract and refractive surgery . 2001,第9期

机译：结膜下类固醇注射液对糖尿病患者白内障手术后眼内炎症和血糖水平的影响。
4. The role of polysaccharide peptide of Ganoderma lucidum as a Potent Protective Vascular Endothelial Cell, Anti Inflammation, and Antioxidant in STEMI and NSTEMI Patients [C] . Djanggan Sargowo, Chamelia Rohadatul Aissy, Umi Kalsum, International Conference on Bioinformatics and Nanomedicine from Natural Resources for Biomedical Research . 2019

机译：Ganoderma lucidum的多糖肽作为有效的保护性血管内皮细胞，抗炎和抗氧化剂在Stemi和Nstemi患者中的作用
5. The safety and tolerability of regadenoson in patients with end stage renal disease. [D] . Rangel, Maria Octavia. 2013

机译：regadenoson在晚期肾病患者中的安全性和耐受性。
6. Ocular tolerability and efficacy of intravitreal and subconjunctival injections of sirolimus in patients with non-infectious uveitis: primary 6-month results of the SAVE Study [O] . Quan Dong Nguyen, Mohamed A Ibrahim, Anthony Watters, 2013

机译：非感染性葡萄膜炎患者玻璃体内和结膜下注射西罗莫司的眼耐受性和疗效：SAVE研究的主要6个月结果
7. Subconjunctival injection of XG-102, a JNK inhibitor peptide, in patients with intraocular inflammation: a safety and tolerability study [O] . Beydoun, Talal, Deloche, Catherine, Perino, Julien, 2014

机译：眼内炎症患者结膜下注射JNK抑制剂XG-102的安全性和耐受性研究

Subconjunctival Injection of XG-102, a JNK Inhibitor Peptide, in Patients with Intraocular Inflammation: A Safety and Tolerability Study

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