Improved resolution in C-13 solid-state spectra through spin-state-selection

摘要

The application of a spin-state-selective coherence transfer experiment (INADEQUATE-SSS) to solid-state NMR spectroscopy is described. Two-dimensional C-13 double-quantum/single-quantum spectra without J splittings in both dimensions lead to enhanced spectral resolution. The method is demonstrated to significantly improve the spectral resolution of the crowded C-1-C-alpha region of two proteins. (c) 2006 Elsevier Inc. All rights reserved.