Experimental and Theoretical Study on the Inclusion Capability of a Fluorescent Indolizine beta-Cyclodextrin Sensor Towards Volatile and Semi-volatile Organic Guest

摘要

Inclusion equilibria of a new fluorescent indolizine modified beta-cyclodextrin were studied in aqueous solution to evaluate its use as a fluorescent chemo-sensor for volatile organic compounds(VOCs).The host compound shows a decrease of the fluorescence intensity by adding adamantanol,benzene,toluene,phenol and p-cresol as guest.The sensing parameter(DELTAI/I_0)was used to show the sensing ability of the host.The formation constant values measured using a spectral displacement method and a specific algorithm treatment are reported.Although the guest binding ability of the sensor is not enhanced by the existence of the hydrophobic cap,this new cyclodextrin sensor shows a very strong sensing ability.The experimental values of the constants were in good agreement with the computed complexation energies,DELTA E,from molecular mechanics modelling of the inclusion process.