Synthesis and antifungal evaluation of novel dicyanoderivatives of rhodanine

摘要

This work describes the synthesis and antifungal evaluation of 5-arylidene-(Z)-2-(1,1-dicyanomethylene)-1,3-thiazol-4-ones 5 obtained from the reaction of 2-(1,1-dicyanomethylene)-1,3-thiazol-4-one 3 and benzaldehydes 4. The starting material 3 was synthesized by a condensation reaction of rhodanine 1 and malononitrile 2. The structures of the obtained products were established by IR, NMR, mass spectrometry, and elemental analysis.