SYNTHESIS OF 8,9-DIHYDRODIPYRAZOLO[3,4-B-4',3'-F][1,5]DIAZOCIN-10(1H)-ONE - A NEW RING SYSTEM

摘要

8,9-Dihydrodipyrazolo[3,4-b:4',3'-f][1,5]diazocin-10(1H)-ones 7 were prepared by cyclization of 1-ethyl-N,3-dimethyl-4-acetamido-N-(1-R(1)-3-R(2)-1H-pyrazol-5-yl)-1H-pyra zole-5-carboxamides 6 by a Bischler-Napieralski cyclization. A complete assignment of the chemical shifts to the carbon atoms of compound 7 was performed by different nmr experiments, such as DEFT and XHDEPT for one-bond C-H correlations and COLOC experiments for long-range C-H correlations. [References: 13]