Trajectories of overweight and body mass index in adulthood and blood pressure at age 53: the 1946 British birth cohort study

摘要

Objective To assess the relationship between patterns of overweight during adulthood and systolic (SBP) and diastolic (DBP) blood pressure (BP) at age 53.Method Data are from 3035 male and female participants of the 1946 British birth cohort study. Body mass index (BMI) was obtained at ages 20, 26,36,43 and 53 years. Censored regression models accounting for medication were used to investigate associations of BP at 53 years with overweight (BMI>25kg/m2) at each age, age at first overweight and conditional weight gain. Sex interactions were also examined.