Localization of phosphatase responsible for hydorlysis of inositol 1,4,5-triphosphate in the olfactory lining of true sturgeons

摘要

The paper presents results of a cytochemical study of localization of phosphatase responsible for hydrolysis of inositol 1,4,5-triphosphate (ITP) in the olfactory lining of true sturgeons (the sturgeon,starred sturgeon,and serlet0.Reaction products as a dark discrete granules are localizedin the apical parts of epithelium,practically in the same manner in all the species studied.The precipitate is found on the plasma membranes of cilia,microvili,and clava of theolfactory cells.Occasionally,the precipitate is also found in the cilia,basal bodies,and rootlets of microvillar cells.The ITP-hydrolyzing phosphatase is supposed torestrict development of transduction process by removing excess messengers from the operating system.The data obtained indicatethat in thetrue sturgeons,the phospholipase cascade of olfactory transduction is concentrated predominatly in thecilia and microvilli of olfactory cells.