A Randomized, Double-blind, Candesartan-controlled, Parallel Group Comparison Clinical Trial to Evaluate the Antihypertensive Efficacy and Safety of Fimasartan in Patients with Mild to Moderate Essential Hypertension

Lee Jang Hoon; Yang Dong Heon; Hwang Jin Yong; Hur Seung Ho; Cha Tae Joon; Kim Ki-Sik; Kim Moo Hyun; Chun Kook Jin; Cha Gwang Soo; Hong Geu Ru; Lee Sang Gon; Kim Dong Soo; Kim Doo Il; Chae Shung Chull

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A Randomized, Double-blind, Candesartan-controlled, Parallel Group Comparison Clinical Trial to Evaluate the Antihypertensive Efficacy and Safety of Fimasartan in Patients with Mild to Moderate Essential Hypertension

机译：一项随机，双盲，坎地沙坦对照，平行组比较的临床试验，以评估菲马沙坦在轻度至中度原发性高血压患者中的降压功效和安全性

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Purpose: A new antihypertensive drug that selectively blocks angiotensin II receptor type 1, fimasartan, has a potent and rapidly acting antihypertensive effect. We investigated the antihypertensive effects of fimasartan 60 and 120 mg and its safety in comparison to 8 mg of candesartan.

机译：目的：一种新的降压药，可选择性阻断1型血管紧张素II受体（菲马沙坦），具有有效且迅速发挥作用的降压作用。我们研究了与8 mg坎地沙坦相比，fimasartan 60和120 mg的抗高血压作用及其安全性。

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来源
《Clinical therapeutics》 |2016年第6期|共13页
作者
Lee Jang Hoon; Yang Dong Heon; Hwang Jin Yong; Hur Seung Ho; Cha Tae Joon; Kim Ki-Sik; Kim Moo Hyun; Chun Kook Jin; Cha Gwang Soo; Hong Geu Ru; Lee Sang Gon; Kim Dong Soo; Kim Doo Il; Chae Shung Chull;
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正文语种 eng
中图分类治疗学;
关键词
angiotensin receptor blocker; candesartan; fimasartan; hypertension;

机译：血管紧张素受体阻滞剂;坎地沙坦;氟马沙坦;高血压;

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1. A Randomized, Double-blind, Candesartan-controlled, Parallel Group Comparison Clinical Trial to Evaluate the Antihypertensive Efficacy and Safety of Fimasartan in Patients with Mild to Moderate Essential Hypertension [J] . Lee Jang Hoon, Yang Dong Heon, Hwang Jin Yong, Clinical therapeutics . 2016,第6期

机译：一项随机，双盲，坎地沙坦对照，平行组比较的临床试验，以评估菲马沙坦在轻度至中度原发性高血压患者中的降压功效和安全性
2. A twelve-week, multicenter, randomized, double-blind, parallel-group, noninferiority trial of the antihypertensive efficacy and tolerability of imidapril and candesartan in adult patients with mild to moderate essential hypertension: the Iberian Mult [J] . Palma-Gamiz JL, Pego M, Contreras EM, Clinical therapeutics . 2006,第12期

机译：一项为期十二周的多中心，随机，双盲，平行组，非劣效性试验，研究了咪达普利和坎地沙坦对成年轻度至中度原发性高血压患者的抗高血压功效和耐受性：伊比利亚多药
3. Effect of Fimasartan versus Valsartan and Olmesartan on Office and Ambulatory Blood Pressure in Korean Patients with Mild-to-Moderate Essential Hypertension: A Randomized, Double-Blind, Active Control, Three-Parallel Group, Forced Titration, Multicenter, Phase IV Study (Fimasartan Achieving Systolic Blood Pressure Target (FAST) Study) [J] . Woo-Baek Chung, Sang-Hyun Ihm, Sung-Won Jang, Drug Design, Development and Therapy . 2020,第1期

机译：Fimasartan对缬沙坦和奥姆森坦对韩国患者患者的办公室和奥姆斯坦坦的影响：随机，双盲，活性控制，三平行组，强制滴定，多中心，第四阶段研究（Fimasartan实现收缩压目标（快）研究）
4. A DOUBLE-BLIND RANDOMIZED PLACEBO-CONTROLLED CLINICAL TRIAL TO INVESTIGATE THE EFFICACY OF TIAMULIN IN THE CONTROL OF PORCINE PROLIFERATIVE ENTEROPATHY (PPE) AND PORCINE COLONIC SPIROCHAETOSIS (PCS) UNDER FIELD CONDITIONS [C] . J. Haugegaard, K. Moller, T.K. Jensen, Congress of the International Pig Veterinary Society . 2000

机译：一种双盲随机安慰剂对照临床试验，探讨硫霉素在野生植物中猪增殖肠病（PPE）和猪结肠螺旋肌肤症（PCS）的疗效
5. A Randomized, Double-blind, Placebo-controlled Clinical Trial Evaluating the Effect of Infliximab on General Cognition in a Population of Depressed Individuals with Bipolar Disorder Type I/II [D] . Pan, Zihang. 2018

机译：一项随机，双盲，安慰剂对照的临床试验，评估英夫利昔单抗对I / II型双相情感障碍抑郁症患者总体认知的影响
6. Effect of Fimasartan versus Valsartan and Olmesartan on Office and Ambulatory Blood Pressure in Korean Patients with Mild-to-Moderate Essential Hypertension: A Randomized Double-Blind Active Control Three-Parallel Group Forced Titration Multicenter Phase IV Study (Fimasartan Achieving Systolic Blood Pressure Target (FAST) Study) [O] . Woo-Baek Chung, Sang-Hyun Ihm, Sung-Won Jang, 2020

机译：菲马沙坦与缬沙坦和奥美沙坦对韩国轻度至中度原发性高血压患者办公室和动态血压的影响：一项随机双盲主动控制三平行组强制滴定多中心IV期研究（Fimasartan实现收缩压目标（FAST）研究）
7. >Effect of Fimasartan versus Valsartan and Olmesartan on Office and Ambulatory Blood Pressure in Korean Patients with Mild-to-Moderate Essential Hypertension: A Randomized, Double-Blind, Active Control, Three-Parallel Group, Forced Titration, Multicenter, Phase IV Study (Fimasartan Achieving Systolic Blood Pressure Target (FAST) Study) [O] . Woo-Baek Chung, Sang-Hyun Ihm, Sung-Won Jang, 2020

机译：> Fimasartan对Valsartan和Olmesartan在韩国患者中的情况下和奥姆森坦的影响：随机，双盲，活性控制，三平行组，强制滴定，多中心，第四阶段研究（Fimasartan实现收缩压目标（快）研究）

A Randomized, Double-blind, Candesartan-controlled, Parallel Group Comparison Clinical Trial to Evaluate the Antihypertensive Efficacy and Safety of Fimasartan in Patients with Mild to Moderate Essential Hypertension

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