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Toxicity estimation of phenolic compounds by bioluminescent bacterium

机译:用生物发光细菌估算酚类化合物的毒性

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Phenolic compounds are environmentally important due to their extensive use in various industries, presence in wastewaters, and potential toxicity. When phenolic compounds reach the activated sludge processes of publicly owned treatment works, they can cause upsets in the operations of the treatment plants. A continuous toxicity testing system was developed based on the bioluminescent bacterium Shk1. The toxicities of 23 phenolic compounds to Shk1 were studied and the 5 min EC50 values were obtained. Quantitative structure-activity relationship models based on the logarithm of the octanol-water partitioning coefficient [log(K-ow)] were established for estimating the toxicity of phenolic compounds and the model validity was verified. [References: 51]
机译:酚类化合物对环境很重要,这是因为它们在各种行业中的广泛使用,废水中的存在以及潜在的毒性。当酚类化合物到达公有处理厂的活性污泥过程时,它们会导致处理厂运行的不正常。基于生物发光细菌Shk1开发了连续毒性测试系统。研究了23种酚类化合物对Shk1的毒性,得出5分钟的EC50值。建立了基于辛醇-水分配系数[log(K-ow)]对数的定量构效关系模型,用于估计酚类化合物的毒性,并验证了该模型的有效性。 [参考:51]

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