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Endovascular repair of external carotid artery disease

机译:颈外动脉疾病的血管内修复

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摘要

Purpose: To review the literature on the endovascular management of external carotid artery (ECA) disease. Methods: A review was conducted of the English-language medical literature from 1985 to 2011 using PubMed, OVID, and EMBASE databases to find all studies involving endovascular management of ECA stenosis. The search identified 21 reports describing endovascular repair of ECA lesions encompassing 56 patients (35 men; mean age 62.6610.5 years) and 58 arteries. Results: The majority of patients (91.1%) were reported to have ipsilateral ICA occlusion, while 55.6% of patients were symptomatic. In the 56 patients, 33 arteries received stents primarily, while 25 had primary balloon angioplasty; 52 cases involved endovascular repair of ECA stenosis, while 4 patients with a normal ECA had a covered stent deployed to exclude the ICA stump. The technical success rate was 98.3%. During the first 30 days after the procedure, 1 (1.8%) stroke was reported, while 5 (8.9%) transient ischemic attacks were also described. During a follow-up period spanning an average 23.8±18.3 months, none of the patients experienced any clinical cerebrovascular event. Two (3.4%) dilated ECAs developed restenosis, while 1 (1.7%) ECA stent occluded at 6 months. Conclusion: Endovascular repair of ECA appears to have low rates of perioperative stroke or death but a high rate of TIAs. The appropriate type of stent and the use of embolic protection need to be established. In the endovascular era, despite the limited data available, this therapeutic approach could be considered a reasonable alternative to conventional open repair, especially in patients with ipsilateral ICA occlusion and concomitant contralateral carotid stenosis or occlusion, an insufficient circle of Willis, and other significant comorbidities.
机译:目的:回顾有关颈外动脉(ECA)疾病血管内治疗的文献。方法:使用PubMed,OVID和EMBASE数据库对1985年至2011年的英语医学文献进行回顾,以查找涉及ECA狭窄的血管内治疗的所有研究。检索发现21篇描述ECA病变血管内修复的报告,涵盖56例患者(35名男性;平均年龄62.6610.5岁)和58条动脉。结果:据报道大多数患者(91.1%)患有同侧ICA闭塞,而有症状的患者占55.6%。在56例患者中,有33条动脉主要接受了支架,而25例进行了原发性球囊血管成形术。 52例涉及ECA狭窄的血管内修复,而4例具有正常ECA的患者则部署了覆盖支架,以排除ICA残端。技术成功率为98.3%。在手术后的前30天内,报告了1次(1.8%)中风,同时还描述了5次(8.9%)短暂性脑缺血发作。在平均23.8±18.3个月的随访期内,没有患者发生任何临床脑血管事件。 2个(3.4%)扩张的ECA发生再狭窄,而1个(1.7%)ECA支架在6个月时闭塞。结论:ECA的血管内修复似乎围手术期卒中或死亡的发生率较低,而TIA的发生率较高。需要确定适当的支架类型和使用栓塞防护装置。在血管内时代,尽管可获得的数据有限,但这种治疗方法仍可被认为是常规开放修补的合理替代方法,尤其是在同侧ICA闭塞并伴有对侧颈动脉狭窄或闭塞,威利斯环圈不足和其他重大合并症的患者中。

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