Gut microbiota-associated bile acid deconjugation accelerates hepatic steatosis in ob/ob mice

摘要

AimNonalcoholic hepatic fat accumulation has been hypothesized to be associated with alterations in gut microbiota composition, although mechanistic explanations for this link are largely insufficient. The aim of this study was to elucidate the microbiota-driven mechanisms involved in the development of nonalcoholic hepatic steatosis.