Solution-Phase Parallel Synthesis of Diverse 1,5-Benzodiazepin-2-ones

摘要

A practical and efficient parallel method has been developed for the synthesis of 1,5-benzodiazepin-2-ones with a large variety of substituents at the 3-,4-,5-,7-,and 8-positions using 1,5-difluoro-2,4-dinitrobenzene as the starting material.All the reactions involved here are highly effective in giving the desired products under mild conditions.