Montmorillonite K-10 mediated Erlenmeyer synthesis of 4-arylmethylene-2-phenyl-5(4H)-oxazolones

摘要

Aromatic aldehydes and hippuric acid in acetic anhydride undergoes classical Erlenmeyer synthesis in the presence of a catalytic amount of Montmorillonite K-10 to afford the corresponding azlactones in excellent yields with high selectivity. The azlactone formation does not proceed in the absence of either acetic anhydride or Montmorillonite.