Effects of regular exercise on the aging immune system: a review.

摘要

Objective: To evaluate the evidence from controlled clinical trials to determine what the effects of regular aerobic and/or resistance exercise were on the immune system in healthy older adults. Data sources: Allied and Complementary Medicine (AMED), CINAHL, EMBASE, MEDLENE, and 7 evidence-based medicine review databases were searched in February 2008 for studies in English of humans, using words pertaining to immunology, exercise, and aging. Reference lists were scanned for further relevant studies. Study selection: Prospective controlled studies were selected if they measured immune variables in older populations (> =50 years); evaluated regular aerobic and/or resistance exercise interventions of > =4 weeks duration; and made baseline measurements of the relevant outcomes. Studies of specific patient-disease groups, including inflammatory diseases, were excluded. From 666 articles identified and 119 full texts scanned 17 studies reported in 19 articles were selected.