Quest for molecular markers in adult soft tissue tumors.

摘要

Soft tissue sarcomas are defined as malignant tumors that arise from nonepithelial extraskeletal tissues including muscle, fat, and fibrous supporting structures. They are a group of uncommon tumors that account for approximately one percent of all cancers.2 Although soft tissue sarcomas can arise anywhere in the body, the majority of them occur in the limb or limb girdle or within the abdomen.1 Currently, the identification of soft tissue sarcomas relies on three methods: the clinical examination of tumor mass and possible site dependent symptoms; imaging detection such as computed tomography (CT) and magnetic resonance imaging (MRI), and histological analysis of biopsy samples. Surgery for localized disease is often curative, alone or in combination with radiotherapy and chemodierapy in selected patients.