Expression of Monocarboxylate Transporters (MCTs) and Basigin and Estrogen Receptor a (ERa) - Mediated Regulation of MCT1 Expression in The Efferent Ductules of Male Reproductive Tract During Postnatal Development

摘要

The male reproductive tract is consisted of the testis and the excurrent ducts. The efferent ductules (ED) are a part of the excurrent ducts, and are a conduit connecting the testis and the head of epididyrrris. As an embryologic homo-logy, the ED have morphological and functional similarities with proximal tubules in the kidney (Clulow et al., 1994). The ED are the places where majority of the testicular fluid is reab-sorbed, resulting in an increase in sperm concentration (Cluow et al., 1994; Clulow et al., 1998).Other than fluid reabsorption, the ED play roles in transport of sperm and the testicullar fluid, secretion and/or sperm and the testicular fluid, secretion and/or absorption of ions and proteins, and reabsorption of testicular proteins (Clulow et al., 1994)