Germ cells possess special properties due to their unique roles. Since germ cells ultimately give rise to all the tissues of a developing animal, they must remain pluripotent, also they are differentiated into highly specialized gametes. Therefore, the research to verify the mechanism of genes involved in germ cell development is highly valuable. The recent developments of large-scale DNA sequencing techniques, micro-array technology and bioinformatics have been enable scientists to identify potential genes, study their patterns of expression and analyze their promoters at the genomic level (Lockhart and Winzeler, 2000). GermOnline being accessible at http://www.Germonline.org is a gateway for germ cell growth and gametogenesis (Wiederkehr et al., 2004a, 2004b). It provides a rapid access to curated information about genes as well asmicroarray expression data implicated in germline development , the mitotic and meiotic cell cycle. gamete formation, and famete function in currently 11 model species such as Homo sapiens, Mus musculus, Rattus norvegicus, Danio rerio, Drosophila melanogaster, caenorhabditis elegans, Arabidopsis thaliana, Schizosaccharo-myces pombe and Saccharomyces cerevisiae.
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