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The distribution of cycles in breakpoint graphs of signed permutations

机译:有符号排列的断点图中循环的分布

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Breakpoint graphs are ubiquitous structures in the field of genome rearrangements. Their cycle decomposition has proved useful in computing and bounding many measures of (dis)similarity between genomes, and studying the distribution of those cycles is therefore critical to gaining insight on the distributions of the genomic distances that rely on it. We extend here the work initiated by Doignon and Labarre [6], who enumerated unsigned permutations whose breakpoint graph contains k cycles, to signed permutations, and prove explicit formulae for computing the expected value and the variance of the corresponding distributions, both in the unsigned case and in the signed case. We also show how our results can be used to derive simpler proofs of other previously known results.
机译:断点图是基因组重排领域中普遍存在的结构。事实证明,它们的循环分解对于计算和限制基因组之间(非)相似性的许多度量非常有用,因此研究这些循环的分布对于深入了解依赖于它的基因组距离的分布至关重要。我们在这里将Doignon和Labarre [6]发起的工作扩展到带符号的排列,Doignon和Labarre列举了断点图包含k个周期的无符号排列,并证明了用于计算期望值和相应分布的方差的显式公式案例和签名案例。我们还将展示如何将我们的结果用于导出其他先前已知结果的更简单证明。

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