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Dynamics of capsule swallowing by healthy young men and capsule transit time from the mouth to the stomach.

机译:健康的年轻人吞咽胶囊的动力学以及胶囊从口腔到胃的转运时间。

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摘要

We examined the dynamics of capsule swallowing by healthy young men using the anterior-posterior view of videofluoroscopy as a first step in a study on capsule swallowing by dysphagic patients. The subjects were 14 healthy men who did not have any complaint of dysphagia. They were asked to swallow a #4 hard gelatin capsule filled with barium sulfate with 15 ml of water during the videofluoroscopic examination. This examination was repeated three times for each subject (total of 42 trials). In four of the 14 subjects, a swallowed capsule was retained at the upper esophageal sphincter, or the broncho-aortic constriction of the esophagus, or the lower esophageal sphincter. Except where retention occurred, the average capsule transit time from the mouth to the stomach was 6.0 +/- 2.4 s. Three of the four subjects who had capsule retention did not realize that the swallowed capsule was retained en route to the stomach. By considering the dynamics of swallowing a capsule with 15 ml of water in healthy men, we should be able to reveal the dynamics of capsule swallowing in dysphagic patients, and the capsule transit time from the mouth to the stomach.
机译:我们使用视频荧光透视的前后视图检查了健康年轻人吞咽胶囊的动力学,这是吞咽困难患者吞咽胶囊研究的第一步。受试者为14名健康男性,他们没有吞咽困难的任何症状。在视频透视检查期间,要求他们吞下装有硫酸钡和15毫升水的#4硬明胶胶囊。对每个受试者重复此检查3次(共42次试验)。在14名受试者中的4名中,吞咽的胶囊保留在食管上括约肌或食道的支气管主动脉狭窄处或食管下括约肌。除了发生滞留的地方,胶囊从口腔到胃的平均通过时间为6.0 +/- 2.4 s。在有胶囊保留的四位受试者中,有三位没有意识到吞咽的胶囊在进入胃的途中被保留了下来。通过考虑健康男性用15 ml水吞服胶囊的动力学,我们应该能够揭示吞咽困难患者吞咽胶囊的动力学以及胶囊从口腔到胃的传播时间。

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