mTOR-Dependent Suppression of Remnant Liver Regeneration in Liver Failure After Massive Liver Resection in Rats

Zhang Dong Xin; Li Chong Hui; Zhang Ai Qun; Jiang Shan; Lai Yan Hua; Ge Xin Lan; Pan Ke; Dong Jia Hong

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mTOR-Dependent Suppression of Remnant Liver Regeneration in Liver Failure After Massive Liver Resection in Rats

机译：大鼠大规模肝切除术后肝功能衰竭中mTOR依赖性肝残余再生的抑制

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Massive hepatectomy often leads to fatal liver failure because of a small remnant liver volume. The aim of this study was to investigate the potential mechanisms leading to liver failure.

机译：大规模肝切除术通常会导致致命的肝衰竭，因为残留的肝脏很小。这项研究的目的是调查导致肝衰竭的潜在机制。

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来源
《Digestive Diseases and Sciences》 |2015年第9期|共12页
作者
Zhang Dong Xin; Li Chong Hui; Zhang Ai Qun; Jiang Shan; Lai Yan Hua; Ge Xin Lan; Pan Ke; Dong Jia Hong;
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正文语种 eng
中图分类消化系及腹部疾病;
关键词
Liver failure; Massive hepatectomy; Liver regeneration; mTOR; Energy status;

机译：肝衰竭;大规模肝切除术;肝再生;mTOR;能量状态;

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1. mTOR-Dependent Suppression of Remnant Liver Regeneration in Liver Failure After Massive Liver Resection in Rats [J] . Zhang Dong Xin, Li Chong Hui, Zhang Ai Qun, Digestive Diseases and Sciences . 2015,第9期

机译：大鼠大规模肝切除术后肝功能衰竭中mTOR依赖性肝残余再生的抑制
2. Preoperative Cholangitis and Future Liver Remnant Volume Determine the Risk of Liver Failure in Patients Undergoing Resection for Hilar Cholangiocarcinoma [J] . Ribero Dario, Zimmitti Giuseppe, Aloia Thomas A., Journal of the American College of Surgeons . 2016,第1期

机译：术前胆管炎和未来肝残余量决定了肝门胆管癌切除术后患者肝功能衰竭的风险
3. Preoperative Cholangitis and Future Liver Remnant Volume Determine the Risk of Liver Failure in Patients Undergoing Resection for Hilar Cholangiocarcinoma Discussion [J] . Nagorney David M., Vauthey Jean-Nicolas, Clary Brian, Journal of the American College of Surgeons . 2016,第1期

机译：术前胆管炎和未来的肝脏残留体积决定了肝胆管癌接受切除患者肝功能衰竭的风险
4. Liver Regenerative Medicine and In Vivo Molecular Imaging for the Study of In Vivo Liver Organogenesis, Liver Disease and Development of New Diagnostics and Therapeutics [C] . Natesh Parashurama AIChE Annual Meeting . 2014

机译：肝脏再生医学和体内分子成像研究体内肝动机，肝病和新诊断和治疗方法的研究
5. Cholangiocyte marker positive and negative fetal liver cells differ significantly in their ability to regenerate the livers of adult rats exposed to retrorsine. [D] . Simper Ronan, Rhonda. 2007

机译：胆管细胞标记物阳性和阴性胎儿肝细胞再生暴露于逆转录酶的成年大鼠肝脏的能力显着不同。
6. Comparison of remnant to total functional liver volume ratio and remnant to standard liver volume ratio as a predictor of postoperative liver function after liver resection [O] . Hee Joon Kim, Choong Young Kim, Young Hoe Hur, 2013

机译：比较残余肝与总功能肝体积比和残余肝与标准肝体积比作为预测肝切除术后肝功能的指标
7. Comparison of remnant to total functional liver volume ratio and remnant to standard liver volume ratio as a predictor of postoperative liver function after liver resection [O] . Hee Joon Kim, Choong Young Kim, Young Hoe Hur, 2013

机译：肝切除术后术后肝功能术后尿量与标准肝体积比的残余物与标准肝体积比的比较
8. THE EFFECT OF VARYING DOSES OF CORTISOL ON THE INCORPORATION OF 3H-THYMIDINE INTO RAT LIVER DNA AND ON THE SYNTHESIS OF FIVE PLASMA PROTEINS IN THE ISOLATED PERFUSED REGENERATING RAT LIVER [R] . Nancy Jean Abbott Lebda 1972

机译：不同剂量的CORTIsOL对3H-甲脒加入大鼠肝脏DNa的影响及离体再灌注大鼠肝脏中5种血浆蛋白质的合成

mTOR-Dependent Suppression of Remnant Liver Regeneration in Liver Failure After Massive Liver Resection in Rats

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