Serotonin syndrome as a complication of fentanyl sedation during esophagogastroduodenoscopy.

摘要

Fentanyl is a medication commonly used to induce and maintain conscious sedation during endoscopic procedures. Fentanyl, a direct serotonin agonist, has many advantages, including its relatively short half-life and lack of histamine-releasing effect [1]. It can precipitate serotonin syndrome when prescribed with other serotogenic medications such as monoamine oxidase inhibitors, lithium, ondansetron, selective serotonin reuptake inhibitors, serotonin, norepi-nephrine reuptake inhibitors, tricyclic antidepressants, amphetamines, and others [2]. To our knowledge, serotonin syndrome has not been described as a complication of fentanyl use during esophagogastroduodenoscopy nor colonoscopy. Here we report the first case of serotonin syndrome secondary to fentanyl in a patient undergoing esophagogastroduodenoscopy