Acylated Iridoid Glycosides from Verbascum lasianthum

摘要

From the roots of Verbascum lasianthum Boiss.ex Bentham 4 catalpol derivatives,6-O-(alpha-L-rhamnopyranosyl)-catalpol(1),verbascoside A [= 6-O-(4"-O-trans-p-methoxycinnamoyl)-alpha-L-rhamnopy-ranosylcatalpol](2).pulverulentoside I [= 6-O-(3"-O-acetyl-2"-O-trans-p-methoxycinnamoyl)-alpha-L-rham-nopyrariosylcatalpol](3),and buddlejoside A_5 [= 6-O-(2"-O-acetyl-3"-O-trans-p-methoxycinnamoyl)-alpha-L-rhamnopyranosylcatalpol](4),as well as aucubin(5)and an aucubin derivative,unduloside III [= 6-O-(3"-O-trans-p-methoxycinnamoyl)-alpha-L-rhamnopyranosylaucubin](6),were isolated and characterized.The structure elucidation of the compounds was established on the basis of spectroscopic evidence.Buddlejoside A_5(4)was found for the first time in the genus Verbascum.