Keratosis palmoplantaris punctata (KPPP) is a rare genodermatosis inherited in autosomal dominant fashion. Clinical findings are multiple, hyperkeratotic, mostly asymptomatic, pinhead-sized papules localized on the palms and soles with progression to hyperkeratotic plaques at pressure sites. A 79-year-old woman presented with a history of hyperkeratotic papules on the palms and soles. Clinical and histopathologic criteria led to the diagnosis KPPP. Identification of causative genes is necessary to permit a better classification and estimation of associated disorders.
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