Shaping the future of Animal AgriGenomicsOriginal Title (non-English) Gestaltung der Zukunft von Genomik in der Tierzucht [German]

摘要

Over the past years and thanks to the development of high throughput genomic tools, whole genome sequencing efforts have enabled a rapid increase in the amount of data available on the genome of livestock species. In addition to their usefulness to better describe genomic structures and functions, new technologies, such as high-quality solutions for interrogating genetic variation in livestock populations, are in fact revolutionizing animal research and breeding: quantitative trait loci can now be mapped in genome wide scans by exploiting Linkage Disequilibrium (LD) and selection decisions will now be based on genomic information, associated with considerable phenotypic information, offering a more cost-effective selection schema. However, while the genomics era should enable the prediction of consequences based on the full DNA sequence of many individuals, new challenges are now to better describe the exact functioning of a genome and better evaluate the contribution of epigenetics to the phenotypic variability of traits of economic interest as it may provide a dynamic and relevant view of possibilities for adaptation to environmental changes.