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Electric Blanket Use and Risk of Thyroid Cancer in the Women's Health Initiative Observational Cohort

机译:妇女健康倡议观察队列中使用电热毯和甲状腺癌的风险

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摘要

Thyroid cancer disproportionally affects more women than men. The aim of this study was to assess whether exposure to extremely low frequency electric magnetic fields from electric blankets (EBs) was associated with the development of thyroid cancer. Data were analyzed from 89,527 women who participated in the Women's Health Initiative Observational Study and who responded to questions concerning prior use of EBs. During a mean follow-up of 12.2 years, 190 incident cases of thyroid cancer were identified. We estimated the hazard ratio (HR) and 95 percent confidence interval (CI) of incident thyroid cancer associated with EB use by Cox's proportional hazard model, adjusted for selected covariates. A majority, 57 percent, of the women in the cohort reported the use of EBs while sleeping and/or for warming the bed before sleep. No association was found between use of EBs and subsequent risk of thyroid cancer (HR = 0.98, 95 percent CI 0.72-1.32). Duration of EB use measured in years, months, or hours had no effect on risk. These results did not change when the cases were limited to papillary thyroid cancer, the most frequently occurring histologic type. The results of this study do not support possible health hazards of EBs in regards to thyroid cancer risk.
机译:甲状腺癌对女性的影响比男性更多。这项研究的目的是评估暴露于电热毯(EB)的极低频电磁场是否与甲状腺癌的发展有关。分析了来自89,527名妇女的数据,这些妇女参加了妇女健康倡议观察性研究并回答了有关先前使用EB的问题。在平均12.2年的随访期间,确定了190例甲状腺癌事件。我们通过Cox比例风险模型(针对选定的协变量进行了调整)估算了与EB使用相关的甲状腺癌事件的风险比(HR)和95%置信区间(CI)。该队列中的大多数女性(57%)报告说,在睡眠时和/或在睡前为床铺加温时使用了EB。在使用EBs和随后的甲状腺癌风险之间未发现关联(HR = 0.98,95%CI 0.72-1.32)。以年,月或小时为单位的EB使用持续时间对风险没有影响。当病例仅限于甲状腺乳头状癌(最常见的组织学类型)时,这些结果没有改变。这项研究的结果不支持EB对甲状腺癌的潜在健康危害。

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