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Intra-aortic balloon counterpulsation - Basic principles and clinical evidence

机译:主动脉内球囊反搏-基本原理和临床证据

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摘要

Intra-aortic balloon pump (IABP) counterpulsation has been the most widely used left ventricular assist device for nearly five decades. Due to diastolic inflation and systolic deflation, coronary blood flow is increased and afterload decreased translating into augmentation of oxygen supply and lowering of oxygen demand. However, IABP may be associated with serious complications, including major bleeding, stroke, local and systemic infections and vascular complications. These might counterbalance the potential beneficial hemodynamic effects.In clinical routine, IABP is mainly used in high-risk patients with acute myocardial infarction, especially when complicated by cardiogenic shock. Further, prophylactic IABP use is frequently performed in patients at high risk for hemodynamic instability undergoing elective percutaneous coronary intervention or coronary artery bypass graft surgery. Current evidence, however, does not fully support routine use of IABP in these settings.This review focuses on the basic principles of IABP and discusses current evidence.
机译:近几十年来,主动脉内球囊反搏一直是使用最广泛的左心室辅助设备。由于舒张期充气和收缩期放气,冠状动脉血流量增加,后负荷减少,转化为氧气供应增加和氧气需求降低。但是,IABP可能伴有严重并发症,包括大出血,中风,局部和全身感染以及血管并发症。这些可能会抵消潜在的有益血流动力学效应。在临床常规中,IABP主要用于急性心肌梗死的高危患者,尤其是合并有心源性休克的患者。此外,在进行选择性经皮冠状动脉介入治疗或冠状动脉搭桥手术的血液动力学不稳定高危患者中,经常使用预防性IABP。但是,目前的证据并不能完全支持在这些情况下常规使用IABP。本文将重点介绍IABP的基本原理,并讨论当前的证据。

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