This issue of TRANSFUSION contains an article by Jobes and colleagues that investigates how long the platelets (PLTs) in cold-stored whole blood function in PLT function tests. However, they pose the question as "How long are the PLTs in fresh whole blood fresh?" It is a strangely worded question, and it does not allay concerns about the relevance of the in vitro data to clinical practice. Fresh, however defined, is not necessarily better than appropriately stored, and PLTs removed from the circulation cannot contribute to "integrated coagulation function."
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