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Maternal and neonatal evaluation of derivated reactive oxygen metabolites (d-ROMs) and biological antioxidant potential in the horse

机译:母体和新生儿对马中的活性氧代谢产物(d-ROM)和生物抗氧化剂潜力的评估

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The aim of the present work was to evaluate derivated reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP) in mares and foals to study perinatal oxidative status. A total of 60 animals were included in the present study. Maternal and foal venous blood samples were collected immediately after delivery along with a sample drawn from one of the umbilical arteries, and plasma samples were evaluated for lactatemia, d-ROMs, and BAP. The t test for unpaired data was applied between mares versus umbilical artery blood versus foals, both for d-ROMs and BAP. The Pearson test with two-tailed P value and a confidence interval of 95% was performed between d-ROMs and BAP and between d-ROMs and lactatemia, both for mares and foals. Finally, the t test for unpaired data was performed between fillies and colts. The t test showed differences between mares versus their own foals versus umbilical artery blood but not foals versus, umbilical artery blood, both for d-ROMs and BAP. A positive correlation was found both in mares and foals between BAP and d-ROMs and in mares between lactatemia and d-ROM. No differences in gender were found in BAP concentration. Our data are in line to previous studies performed in women and cattle. (C) 2015 Elsevier Inc. All rights reserved.
机译:本工作的目的是评估母马和小马驹中的衍生活性氧代谢产物(d-ROM)和生物抗氧化剂潜力(BAP),以研究围产期的氧化状态。本研究共包括60只动物。分娩后立即收集母体和驹静脉血样品,以及从其中一条脐动脉抽取的样品,并评估血浆样品的血乳酸,d-ROM和BAP。对于d-ROM和BAP,在母马与脐动脉血与小马之间进行未配对数据的t检验。对于母马和小马驹,在d-ROM和BAP之间以及d-ROM和乳酸血症之间进行了具有双尾P值和95%置信区间的Pearson测试。最后,在小马驹和小马驹之间进行未配对数据的t检验。 t检验显示,对于d-ROM和BAP,母马与自己的小马驹与脐动脉血之间存在差异,但与小马的驹与脐动脉血之间没有差异。在BAP和d-ROM之间的母马和小马之间以及在乳酸血症和d-ROM之间的母马中都发现了正相关。 BAP浓度未发现性别差异。我们的数据与以前在妇女和牛中进行的研究一致。 (C)2015 Elsevier Inc.保留所有权利。

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