Aspirin may protect against cardiac effects of COX-2 inhibitors,say researchers

摘要

A chemical imbalance that may be corrected with aspirin therapy,could underlie the cardiovascular side effects of cyclo-oxygenase-2 inhibitors,according to results from studies in mice(Cell Metabolism 2005;2:201).The researchers explain that COX-2 inhibitors reduce the production of prostacyclin,which keeps blood vessels open and prevents clots,without affecting production of throm-boxane,a related agent that constricts vessels and promotes clot formation.