Serotonin and sensory signalling from the gastrointestinal lumen

摘要

It is interesting to look through the citation records of classic papers such as this -Bulbring & Lin (1958). It serves as a who's who in serotonin research and catalogues the development of our understanding of the role that 5-HT plays in sensory signalling from the gut lumen,Bulbring had already shown in early publications that the peristaltic reflex was entirely mediated by neural mechanisms within the bowel wall since degenerative section of the extrinsic innervation had no effect on reflex activity (Bulbring et at 1958).