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Modern metal-on-metal hip implants

机译:现代金属对金属髋关节植入物

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摘要

This Technology Overview was prepared using systematic review methodology and summarizes the findings of studies published as of July 15, 2011, on modern metal-on-metal hip implants. Analyses conducted on outcomes by two joint registries indicate that patients who receive metal-on-metal total hip arthroplasty (THA) and hip resurfacing are at greater risk for revision than are patients who receive THA using a different bearing surface combination. Data from these registries also indicate that larger femoral head components have higher revision rates and risk of revision and that older age is associated with increased revision risks of large-head metal-on-metal THA. Several studies noted a correlation between suboptimal hip implant positioning and higher wear rates, local metal debris release, and consequent local tissue reactions to metal debris. In addition, several studies reported elevated serum metal ion concentrations in patients with metal-on-metal hip articulations, although the clinical significance of these elevated ion concentrations remains unknown.
机译:本技术概述是使用系统评价方法编写的,并总结了截至2011年7月15日发表的有关现代金属对金属髋关节植入物的研究结果。由两个联合注册机构进行的结局分析表明,接受金属对金属全髋关节置换术(THA)和髋关节表面置换的患者比使用不同轴承表面组合接受THA的患者发生翻修的风险更大。来自这些登记处的数据还表明,较大的股骨头组件具有较高的翻修率和翻修风险,而年龄较大则与大头金属对金属THA的翻修风险增加相关。几项研究指出,次优的髋关节植入物定位与较高的磨损率,局部金属碎片释放以及随之而来的局部组织对金属碎片的反应之间存在相关性。此外,一些研究报道了金属对金属髋关节的患者血清金属离子浓度升高,尽管这些升高的离子浓度的临床意义仍然未知。

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