Novel strategy to tackle multidrug-resistant pathogens

摘要

A new approach to treating multidrug-resistant Gram-negative infections was reported at the Internationa! Conference on Emerging Infectious Diseases (Atlanta, GA, USA; March, 19-22). Hideki Suzuki and colleagues from ConjuGon Inc, a Madison, Wl-based biotechnology company, have developed a prototype host/plasmid system based on the process of bacterial conjugation. They used a harmless Escherkhia coli donor strain to deliver bactericidal genes on a plasmid into pathogenic bacteria that, when expressed, kill the pathogen.