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首页> 外文期刊>The Lancet >Ep-CAM overexpression in breast cancer as a predictor of survival.
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Ep-CAM overexpression in breast cancer as a predictor of survival.

机译:Ep-CAM在乳腺癌中的过度表达可预测生存率。

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摘要

The epithelial glycoprotein Ep-CAM is overexpressed in colon cancer and breast cancer. We assessed the frequency and prognostic significance of Ep-CAM in tissue specimens from 205 patients with invasive breast cancer, by immunohistochemical staining with a monoclonal antibody specific for the Ep-CAM antigen. Ep-CAM overexpression was found in 35.6% of samples and was associated with poor disease-free and overall survival.
机译:上皮糖蛋白Ep-CAM在结肠癌和乳腺癌中过表达。我们通过用针对Ep-CAM抗原的单克隆抗体进行免疫组织化学染色,评估了205例浸润性乳腺癌患者组织样本中Ep-CAM的频率和预后意义。在35.6%的样本中发现Ep-CAM过表达,并且与无病的疾病和整体生存有关。

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